27. How do you correctly pronounced prion, as in the brain protein? ANSWER: It turns out that, while both pronunciation are used for the word, the brain protein is pronounced pree-on, so put "pree-on" as your answer. "Pry-on" is how you pronounce the prion bird, any of several small petrels (genus Pachyptila of the family Procellariidae, seagull-ish birds) of the southern hemisphere that are bluish gray above and white below.