Vitamin B12 Deficiency (5) 05/04/24

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1) Common risk factor for development of vitamin B12 deficiency *

1 point

a. Crohn's disease

b. Hypertension

c. Excessive consumption of red meat

d. Polycythemia

2) Which of the following medications has been most commonly associated with development of vitamin B12 deficiency? *

1 point

a. Ibuprofen use for > 3 weeks

b. Amlodipine use for > 3 months

c. Sertraline use for > 6 months

d. Metformin use for > 4 months

3) The recommended dietary allowance (RDA) for vitamin B12 in nonpregnant and nonlactating adults?
*

1 point

a. 1.2 µg

b. 1.8 µg

c. 2.4 µg

d. 3.2 µg

4) Common clinical manifestation of vitamin B12 deficiency
*

1 point

a. Leukocytosis

b. Peripheral neuropathy

c. Prolonged constipation (> 7 days)

d. Oliguria

5) Which of the following is recommended in the diagnosis and treatment of vitamin B12 deficiency?
*

1 point

a. All adults > 55 years should be routinely screened for vitamin B12 deficiency

b. Measurement of homocysteine is recommended over measurement of methylmalonic acid in patients with suspected vitamin B12 deficiency who have low-normal serum vitamin B12 levels

c. Oral vitamin B12 supplementation is contraindicated in patients who have had bariatric surgery

d. Intramuscular and oral administration of high-dose vitamin B12 (1-2 mg/d) are equally effective in correcting anemia in patients with vitamin B12 deficiency

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