ASPD Quiz Case 29

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ASPD Quiz Case 29

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A 21 year-old male presents with a progressively enlarging rash on the left side of trunk, face and upper thighs, since childhood. The rash is associated with pruritus - especially when sweating, as well as skin peeling and pain when scratched.

1. What is your most likely diagnosis? *

1 point

Epidermal Naevus

Porokeratosis of Mibelli

Disseminated actinic keratosis

Psoriasis

Disseminated superficial actinic porokeratosis

Which histological feature is characteristic for this condition? *

1 point

Full thickness intra-epidermal atypia of squamous keratinocytes

Well-delimited column of parakeratotic cells

Islands of basaloid cells

Acanthosis of epidermal ridges, dilated blood vessels and perivascular leukocytic infiltrate

Atypical melanocytes

What is the most common type of malignant transformation? *

1 point

Squamous cell carcinoma

Basal cell carcinoma

Melanoma

Mycosis fungoides

Merkel cell carcinoma

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