Every year, millions more road victims are added to the current toll of over 50 million killed and hundreds of millions injured since the first road death 125 years ago last August – a disaster that continues day in and day out in all countries of the world. It is an actual pandemic, affecting primarily our vulnerable and our young, which in addition to the trauma of injury and bereavement has also a devastating economic impact for countries, communities and families. Therefore, during the new Decade of Action 2021-2030 the World Day will have the important role of helping to achieve the 50% road casualty reduction target.