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Restricting feeding to a shorter time window improves metabolic outcomes and athletic performance outcomes mice by
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Supporting the entrainment of peripheral clocks
Decreasing total food intake
Both supporting the entrainment of peripheral clocks and decreasing total food intake
None of the above
Give 2 examples of
essential
and 2 examples of
non-essential
shift work
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Your answer
Would permanent Standard Time or permanent Daylight Savings Time be more beneficial for health outcomes, and why?
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Your answer
In your current understanding, what are some of the societal implications of shift work?
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Your answer
Describe how your role as a professional (scientist, health professional, etc) fits into addressing societal issues. How do you see your work as beneficial to the community?
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Your answer
What is a chronotype?
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Your answer
What environmental factors can affect an individual's circadian biology?
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Your answer
In the liver, thousands of genes exhibit rhythmic expression patterns to optimize for different metabolic needs at different times of day. Do changes in food intake cause changes in
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Liver clock gene rhythmicity
Liver non-clock gene rhythmicity
Both liver clock gene and liver non-clock gene rhythmicity
None of the above
Give two examples of body functions that depends on peripheral clocks?
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Your answer
Give one example of a disease that you expect to be associated with shift work. What peripheral clock(s) do you predict are disrupted in order to cause this disease?
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Your answer
Name 2 genes that are involved in circadian rhythm regulation?
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Your answer
What kind of feedback mechanism is used to regulate circadian rythmns?
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Your answer
Number the following steps in the order of how light entrains the clock from 1 (first step) to 6 (last step).
Each step only occurs once.
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1
2
3
4
5
6
Ca2+ goes into the suprachiasmatic nucleus (SCN).
CREB is phosphorylated.
Glutamate is released.
Intrinsically photosensitive retinal ganglion cells (ipRGCs) are activated.
Light reaches the retina.
Per is transcribed.
1
2
3
4
5
6
Ca2+ goes into the suprachiasmatic nucleus (SCN).
CREB is phosphorylated.
Glutamate is released.
Intrinsically photosensitive retinal ganglion cells (ipRGCs) are activated.
Light reaches the retina.
Per is transcribed.
John has been working at the USA site of his company for several years, but his boss recently notified him that he has been transferred to the company’s UK site. The sun rises earlier in the UK than the US. Select the actogram that would best represent John’s circadian rhythm when he first moves to the UK. Shaded areas represent periods of activity.
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A
B
C
D
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