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ADDISON DISEASE (5 MCQs) 10/05/24
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1) Most common cause of acute adrenocortical insufficiency
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a. Waterhouse-Friderichsen syndrome
b. Anticoagulant therapy
c. Iatrogenic
d. Congenital adrenal hyperplasia
2) Cardinal symptom of chronic adrenocortical insufficiency
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a. Asthenia
b. Hypotension
c. Decreased axillary and pubic hair
d. Hyperpigmentation
e. Abdominal pain
3) Laboratory finding typically present in decreased adrenal reserve
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a. Hyponatremia
b. Elevated serum potassium
c. Reduced serum bicarbonate
d. All
e. None
4) In suspected isolated adrenal hypofunction, 250 ug of cosyntropin given IM. 60 min later, cortisol and aldosterone output are reduced. Basal plasma ACTH is elevated. What is the diagnosis?
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a. Hypopituitarism
b. Miliary TB
c. Small-cell carcinoma of lung
d. Multiple endocrine neoplasia.
5) True about hormone replacement in adrenal insufficiency
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a. Glucocorticoids should be taken with meals
b. Two-thirds of the dose is taken in the afternoon
c. Dose should not be reduced in hypertension
d. Anticonvulsive medications reduce dosage requirements
e. All
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