The Combined Effects of Beetroot Juice and Caloric Restriction on the Brain and Vascular Functions
CRNitrateMRI, Nutrition and Brain Health Research Study, University of Nottingham

We are conducting a research study investigating the combined effects of beetroot juice (dietary nitrate) plus a weight-loss diet (caloric restriction) on the brain and vascular functions. We are interested in recruiting people who are older adults (aged 60-75 years old) living with overweight or obesity (BMI 25-40kg/m2). 

There is evidence to suggest that consuming beetroot juice, a good source of dietary nitrate, whilst restricting your energy intake may improve cognition (e.g., memory), brain blood flow, and blood vessel function.

The study results will help us develop larger and longer studies to test the effects of combining dietary nitrate and energy restriction in people at a higher risk of developing diseases related to cognitive declines, like dementia.

The study will involve drinking beetroot juice and following a diet for 28 days. You will have two brain MRI scan, and measurements of cognitive and vascular function.

On completion, an inconvenience allowance will be paid, and all food will be provided for four weeks.

Thank you for your interest in the CRNitrateMRI study. The University of Nottingham Faculty of Medicine Research Ethics Committee approved the study, reference FMHS 323-0723.

In order to determine your suitability, we need the following information on the form below, or you can email us at Mushari.Alharbi@nottingham.ac.uk

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1. Full Name *
2. Date of birth *
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3. Age
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5. Weight in kg (if not known in kg, please enter in stones and pounds)
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7. What is your BMI?

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12. Do you take any medications or supplements either prescribed by your GP or that you buy?

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13. Are you currently on a specific diet (e.g., vegetarian or vegan)?  

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15. Are you a blood donor? 

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16.  Are you currently in any other research studies, or have you been in any in the last three months? *
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