The 2025 Meeting the Challenge Summit , Advancing Dermatology in Clinical Trials: Expanding Outcome Measures, will be held on December 5-6, 2025 at The Mayflower Hotel in Washington, DC. The Summit will focus on patient-reported outcome measures and clinical trial design, emphasizing integrating patient experiences, particularly across various backgrounds, into dermatologic research. The program will explore best practices in trial design and outcome measurement, and discuss diseases that are inadequately represented in clinical trials. Key discussions will center on how to make clinical trials more representative and impactful, prioritizing patient voices throughout the research process to drive better outcomes in patient care.