Protein Metabolism (Prepared by - Dr Amit Maheshwari)

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This is the quiz on protein metabolism.

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7. Ochronosis” is due to accumulation of

1 point

a. Homogentisic acid

b. Phenylpyruvate

c. Xanthuranate

d. Glyoxylate

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9. The following compound is not a polyamine

1 point

a. Putrescine

b. Ethanolamine

c. Spermine

d. Spermidine

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20. Vasodilator produced by decarboxylation of

1 point

A. Histidine

B Glutamic acid

C Aspartic Acid

D Lysine

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28. Which of the following is true for the glutamate dehydrogenase except

1 point

A It catalyzes oxidative deamination

B Requires NADH or NADPH

C Net removal of alpha amino group of AA to ammonia

D Its an irreversible reaction

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23. Amino acid excreted in cystinuria are all except

1 point

A. Ornithine

B Histidine

C Argininne

D Lysine

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19. Which is elevated in PLP deficiency?

1 point

A FIGLU

B Xanthurenic Acid

C Methyl Malonic acid

D VMA

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22. Pellagra like symptoms seen in

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A Carcinoid syndrome

B Hartnup’s disease

C Both of the above

D None of the above.

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13. GABA is synthesized from

1 point

a. Fumarate

b. Glutamate

c. Histidine

d. Glycine

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2. Which one of the following enzymes of the urea cycle exclusively occurs in the liver?

1 point

a. Ornithine transcarbamoylase

b. Arginosuccinate synthatase

c. Arginosuccinase

d. Arginase

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21. Indoleacetic is seen in urine in case of

1 point

A Alkaptonuria

B Phenylketonuria

C Hartnup’s Disease

D Maple syrup urine disease

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12. The amino acid excreted in urine in Maple syrup urine disease is

1 point

a. Tryptophan

b. Phenylalanine

c. Leucine

d. Arginine

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11. Hyperammonaemia inhibit TCA cycle by depleting

1 point

a. Oxaloacetate

b. Citrate

c. Alpha ketoglutarate

d. Fumarate

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25. True about NO are all except :

1 point

A. Produced from arginine

B Nitric oxide synthase has three isoforms

C Otherwise called EDRF

D Act through C AMP

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14. Oxidative deaminaion occurs in

1 point

a. Cytoplasm of all cells

b. Mitochondria of all cells

c. Cytoplasm of all hepatocytes

d. Mitochondria of hepatocytes

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17. Norepinephrine is converted to epinephrine by

1 point

A Transamination

B Transmethylation

C Transcarboxylation

D Decarboxylation

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6. Ammonia is detoxified in brain to

1 point

a. Urea

b. Glutamine

c. GABA

d. Glutamic acid

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16.Polyamines are synthesized by except

1 point

A. Methionine

B Ornithine

C Arginine

D Cysteine

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15. “ classical pheylketonuria” is caused by deficiency of

1 point

a. Phenylalanine transaminase

b. Phenylalanine hydroxylase

c. Tyrosine transaminase

d. Phenylalanine dehydrogenase

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30. Normal value of Urea

1 point

1. The substance that facilitates protein degradation is

1 point

a. Ubiquinone

b.Phylloquinoneion

c. Menaquinone

d. Ubiquitone

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8. The following tissue produces high amount of serotonin

1 point

a. Brain

b. Liver

c. Heart

d. Intestine

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24. Creatinine, Urea and nitric oxide are derived from which AA

1 point

A. Glycine

B Aspartate

C Arginine

D Citrulline

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3. Elevated homocysteine levels are associated with a risk of

1 point

a. Bronchiectasis

b. Nephritic syndrome

c. Coronary artery disease

d. Diabetes mellitus

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26. Enzyme deficiency in albinism is

1 point

A Tyrosinase

B Tyrosine Hydroxylase

C Phenylalanine Hydroxylase

D Homogentisate Oxidase

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4. The conversion of phenylalanine to tyrosine requires the cofactor

1 point

a. Thioredoxin

b. Biopterin

c. Pteridine

d. Pteroyl

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27. Transamination of oxaloacetate results in the formation of:

1 point

a) Aspartic acid

b) Valine

c) Alanine

d) Serine

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10. Beta alanine is a end product of

1 point

a. Cytosine

b. Tyrosine

c. Serine

d. Glycine

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29. identify the structure

1 point

5. Parkinsonism is associated with an impairment in the synthesis of

1 point

a. Ethanolamine

b. Dopamine

c. Epinephrine

d. Serotonin

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18. Amino acid that can be converted into vitamin :

1 point

A Glycine

B Tryptophan

C Phenylalanine

D Lysine

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