Pharmacon daily Quiz (01 Oct 2018)

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1. Ach is hydrolysed by the enzyme

1 point

Acetyl Cholinesterase

MAO

COMT

Thyrosine hydroxylase

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2. Select correct statement for Botulinum toxin (Food poisoning)

1 point

Exotoxins

Endotoxins

Produced by clostridium botulinum

Both a, b

both b & c

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3. Rate living step in the biosynthesis of Ach.

1 point

Uptake of choline by neuron

Vescular uptake of Ach

Hydrolysis of Ach by AchE

None

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4. A pharmacist has reconstituted a powder dose to form a solution what dose is appropriate when determining a expiration date for this product.

1 point

Identical to the manufacturer’s exp. Date

Not more than 10 days for reconstituted products

Shall not be greater than one year

None

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5. All are the process of extraction of a medicinal active substance from crude drug except

1 point

Maceration

Levigation

Perculation

Infusion

Decoction

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6. The term “Impalpable” refers to a substance that is

1 point

Greasy

not perceptible to the touch

Bad tasting

Tasteless

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7. List of Prescription drugs are included in

1 point

Schedule G

Schedule H

Schedule F

Schedule F1

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8. Pasteurisation of milk is done by

1 point

Holder method (63℃ for 30 minutes)

Flash method (72℃ for 20 sec) followed quickly to 13℃ low

Both

None

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9. Release of NA is inhibited by (Exocutosis)

1 point

Guanethidine

Cocaine

Carbidopa

Metyrosine

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10. Metabolism NA through

1 point

Ach E

MAO

COMT

Both b & c

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11. 100μg equals to I. 1,00,000 mg II. 0.1 mg III. 0.001g

1 point

I only

III only

I & II only

II & III only

I, II & III

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12. If a tablet has an expiration date of July 2018, the Pharmacist may continue to dispose the product

1 point

Upto 6 month after the Expiration date

Only 1st July 2018

Only through 15 July 2018

Only through 31 July 2018

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13. The capacity of the human eye for instilled ophthalmic drops is approximately

1 point

0.01 to 0.05 mL

0.1 mL

0.5 mL

1.0 mL

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14. Solvent used for the extraction process is known as

1 point

Merc

Menstruum

Galenicals

Extrate

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15. Inert insoluble materials that remains after Extraction

1 point

Merc

Menstruum

Galenicals

Extrate

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16. Concentrated infusion is shorter than test infusion about

1 point

5 times

6 times

7 times

8 times

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17. Unorganised drug are extracted by using

1 point

Simple maceration

Maceration with adjustment

Multiple maceration

Decoction

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18. Decoction method of Extraction is used for the

1 point

Hard & woody vegetable drug

Drug having volatile constituents

Thermostable water soluble constituent

Thermostable water Insoluble constituent

Both a,c

a, c & d

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19. Fixed oil from seed & alkaloid are extracted by

1 point

Maceration

Soxhelation hot percolation

Infusion

None

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20. Select false statement regarding synthesis of Ach

1 point

Synthesized from choline + Acetate CoEn A

Synthesized from choline + CoEA

Synthesized in the prefer a enzyme choline acetyl transferate

None

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21. In which phase, study of drug is carried out in human first time

1 point

Phase-I of clinical trials

Phase-II of clinical trials

Phase-III of clinical trials

Phase-IV of clinical trials

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22. Post marketing surveillance of a drug

1 point

Phase-I of clinical trials

Phase-II of clinical trials

Phase-III of clinical trials

Phase-IV of clinical trials

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23. During clinical trials efficacy safety of drug is studied in

1 point

Phase-I of clinical trials

Phase-II of clinical trials

Phase-III of clinical trials

Phase-IV of clinical trials

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24. After which phase completion the drug can be marked after approval

1 point

Phase-I of clinical trials

Phase-II of clinical trials

Phase-III of clinical trials

Phase-IV of clinical trials

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25. Which of the following is excreted in Saliva

1 point

TCs

Ampicillin

Lithium

Chloramphenicol

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26. Principal Neurotransmitter at meuromuscular junction as well all preganglionic fibres.

1 point

Ach

Dopamine

C-HT

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27. Rate limiting step in the Bio-synthesis of Ach

1 point

Uptake of choline by neuron

Uptake of vesicular uptake of Ach

Release of Ach

None

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28. Skeleton muscle contraction is stimulated by

1 point

Nμ Receptor

Nm Receptor

β- receptor

α-receptor

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29. Indirect acting cholinergic drug act by

1 point

Inhibiting the uptake of choline

Inhibiting Ach release

Inhibiting the Acetylcholine sterase

None

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30. Clinical trial for Import & manufacture of new drugs comes under

1 point

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31. Under the Schedule ‘S’, std for cosmetics, finished form shall can form specification laid down by the

1 point

IP (Indian Pharmacopoeia

BIS (Bureau of Indian Std.)

CDSCO

CDRI

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32. A population of cell derived from a single cell are called

1 point

Monoclonal cells

Clones

Protoplasts

Sub culture

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33. The viruses that live as parasites on bacteria are

1 point

Fungi

Commensels

Bacteriophages

Virion

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34. Virus will contain

1 point

Cell wall

Cell membrane

DNA

DNA or RNA

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35. Mesosomes in the bacteria are the part of

1 point

Plasma membrane

Lysosomes

Golgi

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36. The test used to defection of typhoid fever

1 point

WIDAL test

ELISA

Rosewaller test

Western blotting

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37. Killed Bacterial vaccine

1 point

Pertusis

Poliomyelitis

Rabies

None

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38. Humoral Immunity is mediated by

1 point

β-cell

T-cell

RBC

None

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39. Which one is a not a prodrug

1 point

Captopril

Ramipril

Enalapril

All

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40. Select the central sympatholytic drug

1 point

Clonidine

Prazosin

Methyldopa

Both a & c

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41. Wasserman test is used to detect

1 point

Typhoid

Syphilis

Rhematoid arthritis

Typhus

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42. Streptomycin is obtaianed from

1 point

Streptomyces griseus

Streptomyces venezuelae

Streptomyces erythreus

Bacillus polymixa

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