Brighton Collaboration Case Definition Peer Review Form

The revised Brighton Collaboration Case Definition for Anaphylaxis is ready for peer review. Brighton Collaboration encourages members to peer review this template by the end of the day Friday, October 7th 2022.

You can find the revised Anaphylaxis case definition here: https://brightoncollaboration.us/wp-content/uploads/2022/09/Final-Anaphylaxis-Revision-of-the-Brighton-Colloboration-case-definition-10-9-22_for-review47016.pdf 

You can find the original Anaphylaxis case definition here: https://brightoncollaboration.us/anaphylaxis-case-definition-companion-guide/  

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1. Do you agree with the rationale of the revised case definition? *
If "No" or "Do not know", explain why
Comments?
2. Does the preamble clearly describe the intended use of the revised definition? *
If "No" or "Do not know", explain why
Comments?
3. Do you agree with the revised Brighton Collaboration case definition for Anaphylaxis (Table 1)?   *
If "No" or "Do not know", explain why
Comments?
4. Do you agree with level of certainty (LOC) 1?  The LOC 1 criteria remain unchanged for the revised case definition with the exception of including major gastrointestinal signs and laboratory criteria. *
If "No" or "Do not know", explain why
Comments?
5. Do you agree with level of certainty (LOC) 2?  In the revised case definition the LOC 2 criteria has been simplified and now include only major criteria, which must be from at least two different organ systems, excluding a major dermatological criterion. *
If "No" or "Do not know", explain why
Comments?
6. Do you agree with level of certainty (LOC) 3?  LOC 3 can be met by having one major criterion from any of the four systems or raised MCT and one minor criterion from a different system *
If "No" or "Do not know", explain why
Comments?
7. Do you agree with level of certainty (LOC) 4  ? The revised case definition retained this LOC.  *
If "No" or "Do not know", explain why
Comments?
8. Do you agree with level of certainty (LOC) 5?
The revised case definition retained this LOC. 
 *
If "No" or "Do not know", explain why
Comments?
9. Is the revised definition applicable in your setting? *
If "No" or "Do not know", explain why
Comments?
10. Based on your study setting and the procedures, diagnostic requirements for the different levels of certainty in the revised case definition, would you be able to obtain all levels of certainty? *
If "No" or "Do not know", explain why
Comments?
11. Any general comments?
12. Any other comments you would like to share?
A copy of your responses will be emailed to the address you provided.
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