9) An
18-year-old college student presents with a diffuse rash. She also describes
having a headache, fever, and arthralgias for 3 days. On examination, her
temperature is 101.2°F, BP is 120/63 mm Hg, HR is 110 beats per minute, RR is
24 breaths per minute, and oxygen saturation is 98% on room air. The patient is
alert and oriented to person, place, and time. She has nuchal rigidity and
photophobia. Her gums are oozing blood. Her abdomen is soft and nontender and her
skin has a diffuse, petechial rash. You diagnose meningococcemia and
immediately start ceftriaxone and vancomycin. Her laboratory results reveal a
white blood cell count of 13,400/µL, hematocrit 36%, platelets 80,000/ml, PT 60
seconds, international normalized ratio 1.9, and fibrinogen 250 g/L. Which is
the most appropriate next step in management?
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