Third Year B.Pharm Second Sessional Theory Exam 2019-20

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Subject- Biotechnology (BP605 T) Marks- 30

Name of Student *

Roll No. *

PRN Number *

1.Immunity acquired after an infection is *

1 point

Active immunity

All of above

Innate immunity

Passive immunity

2.Inflammation reaction is brought about by *

1 point

Adipose cells

Mast cells

Plasma cells

Macrophages

3.Innate immunity is *

1 point

Inborn immunity

Passive acquired immunity

Active acquired immunity

Both B and C

4. Which is the Ig which crosses placenta and provide passive immunity to newborn? *

1 point

IgE

IgM

IgG

IgA

5.Pollen would most likely evoke which type of hypersensitivity response *

1 point

Immediate type (Type I)

Immune complex (Type III)

Cytotoxic (Type II)

Cell Mediated (Type IV)

6. In vaccine production viruses are grown on_____. *

1 point

Cell culture

Bird embryos

Live animal inoculation

All of above

7.Which MHC molecule recognizes CD8 TC cells? *

1 point

MHC III

MHC II

MHC I

HLA-C

8. Which of the following polypeptide is important for the expression of MHC I on the cell membrane? *

1 point

Interferons

Interleukins

β2-microglobin

Lymphokines

9.The inappropriate response of immune system towards a relatively harmless antigen causing harm to the host is referred as ________. *

1 point

Hypersensitivity

Tolerance

Immunodeficiency

Auto-immune diseases

10.Separation of charged molecules are separated based on varying rates of migration through a solid matrix when subjected to an electric field. *

1 point

Photoreactivation

Gel electrophoresis

Autoradiography

Spectroscopic technique

11.When one bacterium transfers a copy of its plasmid to another bacterium, this is called...... *

1 point

Transduction

Transformation

Vertical gene transfer

Conjugation

12.Transposons were first discovered in ___________. *

1 point

Maize

Mice

Bacteria

Rice

13.Which enzyme catalyzes the excision and insertion events conducted by transposons. *

1 point

Transposase

Transformase

Ligase

Helicase

14.Addition or deletion of bases causes which kind of mutation? *

1 point

Frameshift mutation

Transversion

Transcription

Transition

15.Southern blotting is the technique for the detection of ______. *

1 point

Specific protein in a sample

Specific RNA in a sample

Specific glycolipid in a sample

Specific DNA in a sample

16.Agarose is long un-branched chain of uncharged_____. *

1 point

RNA

Carbohydrate

Vitamins

Protein

17.In gel-electrophoresis fragments are separated on basis of______. *

1 point

Size

Charge

Both A & B

None of these

18. How many types of histone molecules are found in nature? *

1 point

19. Nucleosome is made up of __________. *

1 point

DNA, histone core protein

RNA, histone core protein

DNA, histone core protein, linker H1

RNA, histone core protein, linker H1

20.What is conjugation? *

1 point

Uptake of DNA from hosts

Interchanging of two types of DNA

Transformation of DNA from a donor to recipient cell

Transfer of DNA from recipient to donor

21.Eukaryotes and prokaryotes have either DNA genome or RNA genome. *

1 point

False

True

22.Plasmid replication is dependent on the host cell. *

1 point

True

False

23.All types of mutations are transferable among generations. *

1 point

True

False

24.Ringer's lactate is crystalloid based blood volume expander. *

1 point

False

True

25.Hybridoma technology was discovered in 1975 by two scientists,G. Kohler and C. Milstein. *

1 point

False

True

26. Match the following *

5 points

Body temp

Mucus Membrane

Serum protein

T- lymphocyte

Neutrophils

Physiological barrier

Anatomical Barrier

Cellular immunity

Phagocytic Barrier

Inflammatory Barrier

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