This lecture presents the results of a multi-year collaboration among academic, not-for-profit institution-funded, and independent scholars who represent Moravian and non-Moravian perspectives, and published as an edited volume by Brill Academic Publisher in late 2022. The collaborative work led initially to an international “town and gown” conference at Wake Forest University in the fall of 2020. The conference brought together scholars and religious leaders to examine a rich cultural exchange that came to define the multi-ethnic Moravian-American character of North Carolina in the seminal decades before and after the American Revolution. While unique to the Wachovia region in its specifics, the dynamic Southern “meshwork” of cultural, social, religious, and artistic practices exchanged between Moravians and their white, Indigenous and free and enslaved African neighbors also invites intriguing questions about the character of the new nation  as well as the future of the Moravian Church in a multi-ethnic, diverse South.