東京大学 竹内研究室主催で、下記のオンラインセミナーを開催いたします。奮ってご参加ください。なお、本セミナーは、新学術領域「情報物理学でひもとく生命の秩序と設計原理」が主催するIPBセミナーシリーズの一環として、共同開催となります。セミナーは英語で行われます。

参加される方には事前登録をお願いしておりますので、ご希望の方は本フォームにて登録をお願いいたします。Zoom リンク付の自動返信が送られますので、セミナー開始後でもご登録いただけます。なお、講演者の講演準備の参考・効率化のために、参加登録情報を講演者に提供する可能性がありますので、ご了承ください。

The following online seminar will be held, organized by Takeuchi Lab (Univ. Tokyo) and jointly by Grant-in-Aid for Innovative Areas "Information physics of living matters" (IPB seminar series). The seminar will be given in English.

We ask participants to register beforehand on this page. A reply including a Zoom link will be given automatically, so you can register even after the seminar has started. Please note that the registration information may be provided to the speaker for reference and efficiency in preparing the presentation.

Speaker:
Dr. Deepak Bhat (OIST)

Title:
Dynamics of replisome along bacterial genome

Abstract:
Replisomes are multi-protein complexes that replicate
genomes with remarkable speed and accuracy. In bacteria, two replisomes
initiate replication at a well-defined origin site on the circular
genome, progress in opposite directions, and complete replication upon
encountering each other in a terminal region. Precise features of
replisome dynamics, such as whether their speed is approximately
constant or varies along the genome, are important to determine the
location of their encounter point and the distribution of replication
errors on the genome. But this detailed information is hard to obtain.
We developed a mathematical model to infer the replisome dynamics from
the DNA abundance in a growing bacterial population. I will discuss our
findings in detail in this seminar.